It suggests that the herbicide can cause significant direct genetic damages to chromosome of loach . our experimental results show that loach are susceptible to the induction of nuclear variation 表明不同浓度的精禾草克作用24h可引起泥鳅染色体结构和数目畸变率的显著上升,说明该除草剂对泥鳅染色体具有明显的直接损伤作用。